Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473094 | 0.95 | APEX1 (0.54) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL30478480 | 0.93 | CD40 (0.59) | MEN1KMT2ATIMP3TDP1ALDH1A1 | |
| SCHEMBL11601945 | 0.87 | ALDH1A1 (0.52) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL30388503 | 0.87 | KMT2A (0.75) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL11514021 | 0.85 | TIMP3 (0.72) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL10412672 | 0.85 | APEX1 (0.69) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL11424495 | 0.84 | APEX1 (0.49) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL11765604 | 0.84 | KMT2A (0.65) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL11511236 | 0.84 | TIMP3 (0.59) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL11513442 | 0.83 | CD40 (0.57) | MEN1KMT2ATIMP3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4180587-A | Ureylene phenylene anionic naphthalenesulfonic acids as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4147801-A | UREYLENEBIS/METHYL-PHENYLENE/UREYLENE//DI-1,3,6-NAPHTHALENE TRISULFONIC ACID | AMERICAN CYANAMID COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-4146640-A | SULFONIC ACID AND SECONDARY AMIDE FUNCTIONAL GROUPS | AMERICAN CYANAMID COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
| US-4087548-A | NAPHTHALENE TRISULFONIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1978-05-02 | — | — | US | disclosed |