SCHEMBL1146845

SCHEMBL1146845

CCCCc1ccnc(-c2cc(CCCC)ccn2)c1.[Cu]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
MAPK1 P28482 3/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NFKB1 P19838 4/20 0.40
NFKB2 Q00653 3/20 0.40
RELA Q04206 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
TP53 P04637 1/20 0.40
POLB P06746 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
GAA P10253 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2993441 0.98 SKP2 (0.44) SKP2NPC1RAB9AMAPK1HPGD
SCHEMBL29191290 0.91 SKP2 (0.40) SKP2NPC1RAB9AMAPK1HPGD
SCHEMBL8738529 0.91 NPC1 (0.43) SKP2NPC1RAB9AMAPK1HPGD
Bromide SCHEMBL3735457 0.91 TDP1 (0.43) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL1446914 0.90 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL11798255 0.90 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL7963811 0.90 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL31004368 0.90 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL913250 0.90 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL7964430 0.90 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8405301-B2 Organic electroluminescence element, display device and lighting device KONICA MINOLTA HOLDINGS INC. (JP) 2013-03-26 US disclosed
US-20110095278-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2011-04-28 US disclosed
US-7888859-B2 Organic electroluminescence element, display device and lighting device KONICA MINOLTA HOLDINGS INC. (JP) 2011-02-15 US disclosed
US-20090021147-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-22 US disclosed