Sugi Predict

Sugi Predict / Compounds / SCHEMBL2993441

SCHEMBL2993441

SCHEMBL2993441

CCCCc1ccnc(-c2cc(CCCC)ccn2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SKP2 Q13309 1/20 0.44
▸ NPC1 O15118 4/20 0.44
▸ RAB9A P51151 4/20 0.44
▸ MAPK1 P28482 3/20 0.44
▸ HPGD P15428 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ CCR1 P32246 1/20 0.41
▸ CCR5 P51681 1/20 0.41
▸ CCR8 P51685 1/20 0.41
▸ NFKB1 P19838 4/20 0.41
▸ NFKB2 Q00653 3/20 0.41
▸ RELA Q04206 3/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ L3MBTL1 Q9Y468 3/20 0.41
▸ TP53 P04637 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ TDP1 Q9NUW8 2/20 0.40
▸ GAA P10253 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1146845 0.98 SKP2 (0.43) SKP2NPC1RAB9AMAPK1HPGD
SCHEMBL8738529 0.93 NPC1 (0.43) SKP2NPC1RAB9AMAPK1HPGD
SCHEMBL29191290 0.93 SKP2 (0.40) SKP2NPC1RAB9AMAPK1HPGD
SCHEMBL11798255 0.92 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL7963811 0.92 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL1446914 0.92 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL31004368 0.92 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL913250 0.92 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL7964430 0.92 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1
SCHEMBL529596 0.92 TDP1 (0.46) NPC1RAB9AHPGDSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118225742-A Dissolved oxygen sensor and application thereof 湖南大学 2024-06-21 — — CN claimed
CN-115109009-A Synthesis method of 2-sulfonyl benzothiazole compound 东华理工大学 2022-09-27 — — CN claimed
US-20250320196-A1 APOL1 INHIBITORS AND METHODS OF USES THEREOF MAZE THERAPEUTICS INC (US) 2025-10-16 — — US disclosed
CN-115109009-B Synthesis method of 2-sulfonyl benzothiazole compound 东华理工大学 2023-10-31 — — CN disclosed
CN-114605237-B Preparation method and application of fluoroalkyl ketone compound 武汉大学 2023-02-24 — — CN disclosed
CN-115109009-A Synthesis method of 2-sulfonyl benzothiazole compound 东华理工大学 2022-09-27 — — CN disclosed
US-20220259240-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2022-08-18 — — US disclosed
US-10858334-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-12-08 — — US disclosed
US-10793504-B2 Methods for cross coupling RECURIUM IP HOLDINGS, LLC (US) 2020-10-06 — — US disclosed
US-20190210993-A1 Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-07-11 — — US disclosed
US-20190202769-A1 METHODS FOR CROSS COUPLING RECURIUM IP HOLDINGS, LLC 2019-07-04 — — US disclosed
CN-107074850-A Noval chemical compound 葛兰素史密斯克莱知识产权发展有限公司 2017-08-18 — — CN disclosed
WO-2017061581-A1 METHOD FOR SYNTHESIZING BIPYRIDINE COMPOUND AND METHOD FOR MANUFACTURING PYRIDINE COMPOUND 株式会社神鋼環境ソリューション 2017-04-13 — — WO disclosed
US-8357800-B2 Bipyridine metal complexes for use as light-emitting material SOLVAY (SOCIETE ANONYME) (BE) 2013-01-22 — — US disclosed
US-8097361-B2 Nanotube wiring DOW GLOBAL TECHNOLOGIES LLC (US) 2012-01-17 — — US disclosed
US-20100174078-A1 Bipyridine metal complexes for use as light-emitting material SOLVAY (SOCIETE ANONYME) (BE) 2010-07-08 — — US disclosed
US-20100068621-A1 NANOTUBE WIRING DOW GLOBAL TECHNOLOGIES LLC 2010-03-18 — — US disclosed
US-20090123837-A1 Lithium rechargeable electrochemical cell HPL (HIGH POWER LITHIUM) SA (CH) 2009-05-14 — — US disclosed
US-7361414-B2 Light emitting device and display apparatus using same CANON KABUSHIKI KAISHA (JP) 2008-04-22 — — US disclosed
EP-0411935-A2 Copper radio sensitizers JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1991-02-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10858334-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst PPOX, TST, COX6C SKP2 2061/4885NPC1 4792/4885RAB9A 3699/4885
US-20190202769-A1 METHODS FOR CROSS COUPLING F2, C5, C9 SKP2 1580/4885NPC1 2632/4885RAB9A 1446/4885
US-20190210993-A1 Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst PPOX, TST, COX6C SKP2 2061/4885NPC1 4792/4885RAB9A 3699/4885
US-20250320196-A1 APOL1 INHIBITORS AND METHODS OF USES THEREOF APOL1, APOB, LDLR SKP2 2536/4885NPC1 208/4885RAB9A 2263/4885
US-20220259240-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES RUVBL1, RUVBL2, RPP30 SKP2 2655/4885NPC1 4724/4885RAB9A 579/4885
US-10793504-B2 Methods for cross coupling F2, C5, C9 SKP2 1580/4885NPC1 2632/4885RAB9A 1446/4885
US-20100174078-A1 Bipyridine metal complexes for use as light-emitting material OCIAD2, AP2M1, OCIAD1 SKP2 187/4885NPC1 2306/4885RAB9A 931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.