Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812034 | 0.86 | SIRT2 (0.43) | CYP2C19CYP3A4SIRT2 | |
| SCHEMBL6905227 | 0.86 | SIRT2 (0.43) | CYP2C19CYP3A4SIRT2 | |
| SCHEMBL4804036 | 0.85 | CYP2C19 (0.39) | MAPTALDH1A1CYP2C19CYP3A4TSHR | |
| SCHEMBL4810386 | 0.85 | SIRT2 (0.40) | ALDH1A1CYP2C19CYP3A4TSHRCYP2C9 | |
| SCHEMBL11855720 | 0.83 | PRKCA (0.39) | ALDH1A1CYP2C19CYP3A4PRKCATSHR | |
| SCHEMBL6907567 | 0.82 | CYP3A4 (0.39) | CYP3A4SIRT2 | |
| SCHEMBL4811574 | 0.82 | CYP2C19 (0.41) | MAPTALDH1A1CYP2C19CYP3A4TSHR | |
| SCHEMBL10477317 | 0.81 | CYP1A2 (0.39) | MAPTALDH1A1CYP2C19CYP3A4PRKCA | |
| SCHEMBL28043401 | 0.81 | CYP3A4 (0.36) | ALDH1A1CYP2C19CYP3A4POLBSMN1; SMN2 | |
| SCHEMBL10940755 | 0.81 | CYP2C19 (0.39) | LMNAABCB11MAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182773-A | Novel prostaglandin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |