SCHEMBL11468683

SCHEMBL11468683

Cc1ccc2nn(-c3cc(C)c(O)c(C)c3)nc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.50
NPC1 O15118 11/20 0.50
MEN1 O00255 8/20 0.50
KMT2A Q03164 8/20 0.50
MAPT P10636 7/20 0.50
KDM4E B2RXH2 6/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
ALDH1A1 P00352 5/20 0.50
HPGD P15428 3/20 0.50
TP53 P04637 3/20 0.50
GAA P10253 2/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
HSD17B10 Q99714 1/20 0.50
LMNA P02545 2/20 0.46
MCL1 Q07820 1/20 0.46
ATM Q13315 2/20 0.41
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
ALOX5 P09917 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11469488 0.84 PPARG (0.54) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL11459762 0.83 NPC1 (0.49) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL11466750 0.83 RAB9A (0.53) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL11458150 0.81 NPC1 (0.45) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL10424691 0.80 NPC1 (0.55) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL3221922 0.80 NPC1 (0.73) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL3226780 0.77 KDM4E (0.63) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL25753109 0.76 NPC1 (0.50) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL13492184 0.76 NPC1 (0.54) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL7086885 0.75 NPC1 (0.47) RAB9ANPC1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4235999-A Bichromophoric benzotriazole-styrene ester ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1980-11-25 US disclosed
US-4187229-A Bis-benzotriazole compounds EASTMAN KODAK COMPANY (US) 1980-02-05 US disclosed
US-4174321-A POLYMERIC MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1979-11-13 US disclosed
US-4159270-A Bichromophoric benzotriazole-styrene ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-06-26 US disclosed
US-4127501-A BENZOXAZOLE, BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTRIAZOLE OR INDOLE DERIVATIVES EASTMAN KODAK COMPANY (US) 1978-11-28 US disclosed
US-4085089-A Benzotriazole ultraviolet stabilizing compounds and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-04-18 US disclosed
US-4073745-A Multichromophoric benzotriazole ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-02-14 US disclosed
US-4070337-A Bichromophoric benzotriazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed
US-4070339-A Bichromophoric benzotriazole-styrene ester ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed
US-3981884-A POLYMERS EASTMAN KODAK COMPANY (US) 1976-09-21 US disclosed