Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531177 | 0.84 | KMT2A (0.67) | MEN1KMT2ANPSR1CA12CA1 | |
| SCHEMBL11534293 | 0.82 | MEN1 (0.60) | MEN1KMT2AEPHX2NPSR1POLB | |
| SCHEMBL11468753 | 0.81 | EPHX2 (0.65) | MEN1KMT2AEPHX2HPGDHTT | |
| SCHEMBL11462358 | 0.80 | EPHX2 (0.58) | MEN1KMT2AEPHX2NPSR1CA12 | |
| SCHEMBL2920100 | 0.79 | MEN1 (0.72) | MEN1KMT2AEPHX2NPSR1CA12 | |
| SCHEMBL11531653 | 0.79 | MEN1 (0.72) | MEN1KMT2AEPHX2POLBKDM4E | |
| SCHEMBL6689250 | 0.79 | ALDH1A1 (0.70) | KMT2ALMNACA12CA1CA2 | |
| SCHEMBL11534382 | 0.77 | MEN1 (0.65) | MEN1KMT2AEPHX2POLBKDM4E | |
| SCHEMBL5261643 | 0.76 | KMT2A (0.72) | MEN1KMT2AEPHX2NPSR1CA12 | |
| SCHEMBL1939359 | 0.76 | KMT2A (0.72) | MEN1KMT2AEPHX2NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183927-A | Substituted phenylthioalkylamines and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1980-01-15 | — | — | US | claimed |
| US-4183927-A | Substituted phenylthioalkylamines and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1980-01-15 | — | — | US | disclosed |
| US-4155907-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4141983-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| US-4134996-A | METHOD FOR INHIBITING ADP-INDUCED PLATELET AGGREGATION USING PHENYLTHIOALKYLAMINES | THE DOW CHEMICAL COMPANY (US) | 1979-01-16 | — | — | US | disclosed |