Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472070 | 1.00 | TSHR (0.50) | TSHRNR1I2PTGESALOX5TDP1 | |
| SCHEMBL11471689 | 1.00 | TSHR (0.50) | TSHRNR1I2PTGESALOX5TDP1 | |
| SCHEMBL11478307 | 1.00 | TSHR (0.50) | TSHRNR1I2PTGESALOX5TDP1 | |
| SCHEMBL11473168 | 1.00 | TSHR (0.50) | TSHRNR1I2PTGESALOX5TDP1 | |
| SCHEMBL11467633 | 1.00 | TSHR (0.50) | TSHRNR1I2PTGESALOX5TDP1 | |
| SCHEMBL11472114 | 1.00 | TSHR (0.50) | TSHRNR1I2PTGESALOX5TDP1 | |
| SCHEMBL11467657 | 0.88 | SLC40A1 (0.48) | TSHRNR1I2PTGESALOX5TDP1 | |
| SCHEMBL11473298 | 0.85 | TSHR (0.53) | TSHRTDP1SLC40A1ALDH1A1HPGD | |
| SCHEMBL11470920 | 0.85 | GLO1 (0.44) | NR1I2PTGESALOX5TDP1SLC40A1 | |
| SCHEMBL11480688 | 0.85 | GLO1 (0.44) | NR1I2PTGESALOX5TDP1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100163-A | Substituted 8-sulfonamidoquinolines | GENERAL MILLS CHEMICALS, INC. (US) | 1978-07-11 | — | — | US | claimed |
| US-4209419-A | Certain sulfonamidoquinolines, metal complexes thereof, and solutions containing such sulfonamidoquinolines and metal complexes | HENKEL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4100163-A | Substituted 8-sulfonamidoquinolines | GENERAL MILLS CHEMICALS, INC. (US) | 1978-07-11 | — | — | US | disclosed |