Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.60 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30925467 | 0.84 | TDP1 (0.72) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL27214223 | 0.84 | TDP1 (0.72) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL13485953 | 0.78 | TDP1 (0.73) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL11997128 | 0.78 | SLC40A1 (0.82) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL11468730 | 0.77 | TDP1 (0.63) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL7196771 | 0.77 | TDP1 (1.00) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL11997124 | 0.75 | SLC40A1 (0.81) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL11973000 | 0.75 | SLC40A1 (1.00) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL7195142 | 0.75 | SLC40A1 (0.79) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL11973466 | 0.75 | SLC40A1 (1.00) | TDP1KMT2AMEN1SLC40A1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100163-A | Substituted 8-sulfonamidoquinolines | GENERAL MILLS CHEMICALS, INC. (US) | 1978-07-11 | — | — | US | claimed |
| US-4209419-A | Certain sulfonamidoquinolines, metal complexes thereof, and solutions containing such sulfonamidoquinolines and metal complexes | HENKEL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4100163-A | Substituted 8-sulfonamidoquinolines | GENERAL MILLS CHEMICALS, INC. (US) | 1978-07-11 | — | — | US | disclosed |