Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.67 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | CKS1B | P61024 | 1/20 | 0.67 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | G6PD | P11413 | 1/20 | 0.60 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11997128 | 0.90 | SLC40A1 (0.82) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL11997124 | 0.87 | SLC40A1 (0.81) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL27214217 | 0.85 | SLC40A1 (0.82) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL30925445 | 0.85 | SLC40A1 (0.82) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL13485953 | 0.85 | TDP1 (0.73) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL30925502 | 0.84 | TDP1 (0.72) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL27214196 | 0.84 | TDP1 (0.72) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL11973308 | 0.82 | SLC40A1 (1.00) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL11973620 | 0.82 | SLC40A1 (0.73) | TDP1KMT2AMEN1SLC40A1HTT | |
| SCHEMBL11485539 | 0.82 | SLC40A1 (0.74) | TDP1KMT2AMEN1SLC40A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200046-B2 | Reporter system for high throughput screening of compounds and uses thereof | CORNELL UNIVERSITY (US) | 2015-12-01 | — | — | US | disclosed |
| US-9200046-B2 | Reporter system for high throughput screening of compounds and uses thereof | CORNELL UNIVERSITY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20130005666-A1 | REPORTER SYSTEM FOR HIGH THROUGHPUT SCREENING OF COMPOUNDS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130005666-A1 | REPORTER SYSTEM FOR HIGH THROUGHPUT SCREENING OF COMPOUNDS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2013-01-03 | — | — | US | disclosed |
| US-6528187-B1 | Luminescence element comprising pair of electrodes having formed therebetween plurality of organic compound thin film layers comprising electron-transporting layer which comprises specified compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005666-A1 | REPORTER SYSTEM FOR HIGH THROUGHPUT SCREENING OF COMPOUNDS AND USES THEREOF | NFE2, NFE2L2, UBE2N | TDP1 3874/4885KMT2A 2699/4885MEN1 3331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.