Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265379 | 1.00 | THRB (0.44) | THRBTHRAMAPTSMN1; SMN2PRSS1 | |
| SCHEMBL11459835 | 0.96 | THRB (0.47) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11266718 | 0.93 | THRB (0.48) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11261251 | 0.92 | THRB (0.50) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11249685 | 0.88 | KMT2A (0.41) | MAPTSMN1; SMN2PRSS1ACRKMT2A | |
| SCHEMBL13367301 | 0.85 | MGLL (0.44) | MAPTSMN1; SMN2PRSS1ACRKMT2A | |
| SCHEMBL10588486 | 0.84 | KMT2A (0.40) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL10588481 | 0.84 | KMT2A (0.40) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL9659436 | 0.84 | NPC1 (0.55) | THRBTHRAMAPTSMN1; SMN2PRSS1 | |
| SCHEMBL9660630 | 0.84 | NPC1 (0.55) | THRBTHRAMAPTSMN1; SMN2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200580-A | Dioxanylphenyl benzoate liquid crystal compounds | TIMEX CORPORATION (US) | 1980-04-29 | — | — | US | disclosed |