Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469998 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL11129884 | 0.83 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL11463181 | 0.82 | ALDH1A1 (0.59) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL14412438 | 0.81 | POLB (0.72) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL9703278 | 0.80 | CA1 (0.48) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL9703275 | 0.80 | CA1 (0.48) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL11883912 | 0.79 | POLB (0.69) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL1199964 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL27834965 | 0.78 | CA2 (0.48) | KDM4EALDH1A1MAPTKMT2ACA1 | |
| SCHEMBL10752864 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1MAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187226-A | 1-(ALKOXYALKYLSULFONYLPHENYL/-3-PHENYLPYRAZOLINES, OPTICAL BRIGHTENERS | BASF AKTIENGESELLSCHAFT (DE) | 1980-02-05 | — | — | US | disclosed |
| US-4183851-A | OPTICAL BRIGHTENERS | BASF AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |
| US-4164500-A | OPTICAL BRIGHTENERS | BASF AKTIENGESELLSCHAFT (DE) | 1979-08-14 | — | — | US | disclosed |
| US-4129563-A | OPTICAL BRIGHTENERS | BASF AKTIENGESELLSCHAFT (DE) | 1978-12-12 | — | — | US | disclosed |