Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 6/20 | 0.34 |
| ▸ | MAOB | P27338 | 6/20 | 0.34 |
| ▸ | AOC2 | O75106 | 5/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489987 | 0.78 | CA2 (0.37) | CA2 | |
| SCHEMBL8524032 | 0.74 | NISCH (0.54) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL6265801 | 0.74 | NISCH (0.49) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL2502594 | 0.71 | NISCH (0.53) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL2462764 | 0.70 | NISCH (0.49) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL3080227 | 0.70 | NISCH (0.56) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL6747489 | 0.70 | CA2 (0.44) | MAOAMAOBAOC2CA2 | |
| SCHEMBL23183087 | 0.67 | NISCH (0.53) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL2597074 | 0.67 | NISCH (0.58) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL4954350 | 0.67 | NISCH (0.53) | NISCHMAOAMAOBAOC2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018674-A1 | Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |