Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | AOC2 | O75106 | 5/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080227 | 0.78 | NISCH (0.56) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL30298419 | 0.76 | NISCH (0.50) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL4954350 | 0.75 | NISCH (0.53) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL2502594 | 0.75 | NISCH (0.53) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL23183087 | 0.75 | NISCH (0.53) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL7616087 | 0.75 | NISCH (0.53) | NISCHMAOAMAOBAOC2DAO | |
| SCHEMBL19121185 | 0.75 | NISCH (0.49) | NISCHMAOAMAOBTSHRNPC1 | |
| SCHEMBL7086543 | 0.75 | NISCH (0.67) | NISCHHPGDTSHRNPC1RAB9A | |
| SCHEMBL3850027 | 0.73 | NISCH (0.51) | NISCHMAOAMAOBAOC2NPC1 | |
| SCHEMBL28787079 | 0.72 | NISCH (0.54) | NISCHMAOAMAOBTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850251-A | 3,4-methylenedioxyacetophenone imidazole oxime ether derivative, preparation method and application thereof, and medicine for treating Alzheimer's disease | 西北农林科技大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115850251-A | 3,4-methylenedioxyacetophenone imidazole oxime ether derivative, preparation method and application thereof, and medicine for treating Alzheimer's disease | 西北农林科技大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-115175905-A | ZESTE enhancer homolog 2 inhibitors and uses thereof | 四川海思科制药有限公司 | 2022-10-11 | — | — | CN | disclosed |
| US-9220787-B2 | Vitamin E conjugates, and their uses as antioxidants and prodrug delivery vehicles | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2015-12-29 | — | — | US | disclosed |
| US-20130210702-A1 | Vitamin E Conjugates, and Their Uses as Antioxidants and Prodrug Delivery Vehicles | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2013-08-15 | — | — | US | disclosed |
| WO-2011146589-A2 | VITAMIN E CONJUGATES, AND THEIR USES AS ANTIOXIDANTS AND PRODRUG DELIVERY VEHICLES | BOARD OF SUPERVISORS OF LOUSIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210702-A1 | Vitamin E Conjugates, and Their Uses as Antioxidants and Prodrug Delivery Vehicles | TTPA, VSIR, FOLR1 | NISCH 477/4885MAOA 1172/4885MAOB 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.