Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 13/20 | 0.69 |
| ▸ | AKR1C2 | P52895 | 13/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.69 |
| ▸ | CDC42 | P60953 | 1/20 | 0.69 |
| ▸ | RAC1 | P63000 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11721423 | 0.98 | AKR1C3 (0.67) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL4679446 | 0.90 | AKR1B1 (0.69) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL10025981 | 0.90 | AKR1B1 (0.69) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL1217681 | 0.90 | AKR1B1 (0.69) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL12431128 | 0.90 | AKR1B1 (0.69) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL30717241 | 0.90 | AKR1B1 (0.69) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| Hydrochloric Acid SCHEMBL27401798 | 0.89 | AKR1B1 (0.67) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11476933 | 0.86 | AKR1C3 (0.68) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11764188 | 0.86 | PTGS2 (0.55) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| Acetic Acid SCHEMBL28429217 | 0.85 | EIF4A3 (0.53) | AKR1C3AKR1C2PTGS2PTGS1CDC42 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207241-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS AND ANTIPRURITIC AGENTS | SYNTEX CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4132804-A | 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID | THE UPJOHN COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4097674-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTIPRURITIC AGENTS, ANALGESICS | SYNTEX CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4051233-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-4048330-A | Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia | SYNTEX CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4009197-A | 2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof | SYNTEX CORPORATION (PM) | 1977-02-22 | — | — | US | disclosed |
| US-3998966-A | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof | SYNTEX CORPORATION (PM) | 1976-12-21 | — | — | US | disclosed |
| US-3980699-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-09-14 | — | — | US | disclosed |
| US-3978124-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
| US-3978116-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
| US-3958012-A | ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIVITY | SYNTEX CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |