Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168656 | 0.77 | PTPRC (0.49) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL3164860 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL10900077 | 0.77 | CYP2A6 (0.48) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL13575388 | 0.77 | PTPRC (0.53) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11447916 | 0.75 | MKNK1 (0.50) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL29551674 | 0.73 | CA12 (0.61) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL3633054 | 0.73 | CA12 (0.61) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL11159194 | 0.73 | PDE3B (0.47) | PDE3BPDE3ATRPA1NOTUMPPARG | |
| SCHEMBL26986890 | 0.73 | ESR2 (0.51) | KDM4EALDH1A1MCL1TRPA1 | |
| SCHEMBL21904914 | 0.73 | L3MBTL1 (0.48) | KDM4EALDH1A1MAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242515-A | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo-[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0017438-A1 | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo(4,3-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4209626-A | Substituted 6-phenyl-1,2,4-triazolo[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |