Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluquazone SCHEMBL43464 | 0.89 | MAPT (0.58) | LMNAMAPTTP53RXFP1 | |
| SCHEMBL11480424 | 0.87 | MAPT (0.57) | LMNAMAPTTP53RXFP1KDM4E | |
| SCHEMBL11470963 | 0.87 | MAPT (0.57) | LMNAMAPTTP53RXFP1KDM4E | |
| SCHEMBL11468011 | 0.86 | MAPT (0.56) | LMNAMAPTTP53RXFP1KDM4E | |
| SCHEMBL11472800 | 0.85 | MAPT (0.59) | LMNAMAPTTP53RXFP1KDM4E | |
| SCHEMBL11462861 | 0.84 | MAPT (0.59) | LMNAMAPTTP53RXFP1KDM4E | |
| Fluquazone SCHEMBL28193448 | 0.83 | MAPT (0.57) | LMNAMAPTTP53RXFP1KDM4E | |
| SCHEMBL11462119 | 0.82 | MAPT (0.56) | LMNAMAPTTP53RXFP1 | |
| SCHEMBL11157753 | 0.80 | MAPT (0.61) | LMNAMAPTTP53RXFP1KDM4E | |
| SCHEMBL11638904 | 0.80 | LMNA (0.66) | LMNAMAPTTP53RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |