Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1B | Q92523 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181662 | 0.83 | CES2 (0.79) | CPT1BCES2ESR1ESR2LMNA | |
| SCHEMBL5917993 | 0.79 | CES2 (0.75) | CES2LMNAMAPTHPGDHTT | |
| SCHEMBL1454951 | 0.78 | LMNA (0.60) | CPT1BCES2ESR1ESR2LMNA | |
| Hydroquinone SCHEMBL7948998 | 0.78 | LMNA (0.60) | CPT1BCES2ESR1ESR2LMNA | |
| SCHEMBL7532519 | 0.77 | MAPT (0.52) | CPT1BCES2ESR1ESR2LMNA | |
| SCHEMBL6522491 | 0.77 | CES2 (0.71) | CES2MAPTCA1CA2MEN1 | |
| SCHEMBL11718383 | 0.77 | CES2 (0.71) | CES2LMNAMAPTHPGDHTT | |
| SCHEMBL8386482 | 0.77 | CES2 (0.71) | CES2MAPTCA1CA2MEN1 | |
| SCHEMBL5918066 | 0.77 | CES2 (0.71) | CES2LMNAMAPTPKMHPGD | |
| SCHEMBL204420 | 0.77 | CPT1B (0.52) | CPT1BCES2ESR1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207234-A | 4-Unsubstituted azetidinone derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |