Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | CD38 | P28907 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464771 | 0.88 | CYP3A4 (0.56) | KMT2AMEN1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11469457 | 0.87 | CYP3A4 (0.67) | KMT2AMEN1CYP3A4HPGDTSHR | |
| SCHEMBL11464531 | 0.87 | CYP3A4 (0.55) | KMT2AMEN1NPSR1TDP1CYP3A4 | |
| SCHEMBL11461786 | 0.87 | MEN1 (0.61) | KMT2AMEN1NPSR1CYP3A4CYP1A2 | |
| SCHEMBL11469285 | 0.87 | POLB (0.57) | KMT2AMEN1NPSR1TDP1CYP3A4 | |
| SCHEMBL11463533 | 0.86 | TSHR (0.59) | KMT2AMEN1NPSR1TDP1CYP3A4 | |
| SCHEMBL7303219 | 0.85 | LMNA (0.66) | KMT2AMEN1CYP3A4ALDH1A1MAPT | |
| SCHEMBL11539010 | 0.85 | KMT2A (0.67) | KMT2AMEN1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11472571 | 0.84 | F10 (0.60) | KMT2AMEN1TDP1CYP3A4CD38 | |
| SCHEMBL11464515 | 0.83 | CYP2D6 (0.57) | KMT2AMEN1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4236015-A | ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS, FUNGICIDES | WESTWOOD PHARMACEUTICALS, INC. (US) | 1980-11-25 | — | — | US | claimed |