Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | CD38 | P28907 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541657 | 0.91 | MEN1 (0.76) | KMT2AMEN1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL11538930 | 0.88 | MEN1 (0.76) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11538807 | 0.87 | KMT2A (0.67) | KMT2AMEN1RAB9AHTTNPC1 | |
| SCHEMBL11537127 | 0.87 | MEN1 (0.67) | KMT2AMEN1SMN1; SMN2POLBTAAR1 | |
| SCHEMBL11535044 | 0.87 | MEN1 (0.78) | KMT2AMEN1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL11538736 | 0.87 | KMT2A (0.63) | KMT2AMEN1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL11540163 | 0.86 | MEN1 (0.60) | KMT2AMEN1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL11536064 | 0.85 | KMT2A (0.65) | KMT2AMEN1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL11471648 | 0.85 | KMT2A (0.57) | KMT2AMEN1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL11537243 | 0.84 | KMT2A (0.67) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160097-A | INTERMEDIATES FOR FUNGICIDAL AND ANTIINFLAMMATORY 4-SUBSTITUTED IMIDAZO(1,2-A)QUINOXALINES | WESTWIND PHARMACEUTICALS, INC. (US) | 1979-07-03 | — | — | US | claimed |