Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11467829 | 0.98 | ALDH1A1 (0.43) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL11499454 | 0.83 | HDAC6 (0.44) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| Hydrochloric Acid SCHEMBL11470685 | 0.82 | HDAC6 (0.43) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| Hydrochloric Acid SCHEMBL11483721 | 0.79 | HDAC6 (0.43) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL11485429 | 0.79 | HDAC6 (0.50) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| Hydrochloric Acid SCHEMBL11471583 | 0.78 | HDAC6 (0.42) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL11498371 | 0.77 | SSTR5 (0.42) | HDAC6HDAC2HDAC8TBXA2RCHRM2 | |
| SCHEMBL11475559 | 0.77 | DCUN1D1 (0.41) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| Hydrochloric Acid SCHEMBL11486433 | 0.76 | SSTR5 (0.42) | HDAC6HDAC2HDAC8TBXA2RCHRM2 | |
| Hydrochloric Acid SCHEMBL11479030 | 0.76 | HDAC6 (0.41) | HDAC6HDAC2HDAC8TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181657-A | 2-Aminooctahydroindolo[2,3-a]quinolizines useful in treating cardiovascular disorders | MILES LABORATORIES, INC. (US) | 1980-01-01 | — | — | US | disclosed |