SCHEMBL114753

SCHEMBL114753

CCCCC[Si](OC)(OC)OC

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.61
TSHR P16473 4/20 0.39
THRB P10828 1/20 0.39
EPHX1 P07099 1/20 0.34
SLC22A1 O15245 2/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LPAR2 Q9HBW0 3/20 0.31
LPAR3 Q9UBY5 3/20 0.31
ALDH1A1 P00352 3/20 0.30
DNM1 Q05193 3/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9931816 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1
Ammonia Solution, Strong SCHEMBL7641868 0.97 LMNA (0.59) LMNATSHRTHRBEPHX1SLC22A1
SCHEMBL17003993 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1
SCHEMBL304612 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1
Hexane SCHEMBL6049081 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1
SCHEMBL35912 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1
SCHEMBL6756329 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1
SCHEMBL377101 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1
SCHEMBL1780545 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1
SCHEMBL11213774 0.97 LMNA (0.65) LMNATSHRTHRBEPHX1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3329 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES CHAN, Hardy Wai Hong (TW) 2026-01-01 US claimed
EP-4437017-B1 AQUEOUS POLYMER COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2025-09-24 EP claimed
EP-3935114-B1 PROTECTIVE COATING COMPOSITION AND COATED METALLIC SUBSTRATE COMPRISING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2025-07-16 EP claimed
WO-2025133002-A1 MICROPOROUS SIO2 PARTICLES MERZ + BENTELI AG (CH) 2025-06-26 WO claimed
US-12336096-B1 Dielectric, copper clad laminate, circuit board, method for manufacturing copper clad laminate NIPPON PILLAR PACKING CO., LTD. (JP) 2025-06-17 US claimed
CN-119306225-A Nanometer silicon dioxide with controllable hydrophobicity and preparation method and application thereof 中国石油天然气集团有限公司 2025-01-14 CN claimed
CN-119307246-A Modified nano silicon dioxide continuous blending fracturing fluid and preparation and use thereof 中国石油天然气集团有限公司 2025-01-14 CN claimed
CN-119265931-A Environment-friendly starch slurry for sizing glass fiber yarns for high-density weaving and preparation method and application thereof 江苏新瑞贝生物科技股份有限公司 2025-01-07 CN claimed
WO-2024263122-A1 SUPERHYDROPHOBIC AND SUPEROLEOPHILIC COMPOSITE SPONGE MATERIAL AND THE PRODUCTION METHOD THEREOF AKDENIZ UNIVERSITESI (TR) 2024-12-26 WO claimed
US-20240417558-A1 AQUEOUS POLYMER COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-12-19 US claimed
EP-0701590-A1 PRIMER COMPOSITION FOR IMPROVING THE BONDING OF A URETHANE ADHESIVE TO NON-POROUS SUBSTRATES Gurit-Essex AG (CH) 1996-03-20 EP claimed
EP-0674237-A1 Electrostatic image-developing toner, fine powdery titanium oxide, and hydrophobic fine powdery titanium oxide CANON KABUSHIKI KAISHA (JP) 1995-09-27 EP claimed
EP-0669385-A1 Silicone release agent and method DOW CORNING CORPORATION (US) 1995-08-30 EP claimed
WO-1994029390-A1 PRIMER COMPOSITION FOR IMPROVING THE BONDING OF A URETHANE ADHESIVE TO NON-POROUS SUBSTRATES ESSEX SPECIALTY PRODUCTS, INC. (US) 1994-12-22 WO claimed
EP-0579453-A2 Masonry treating composition and method DOW CORNING CORPORATION (US) 1994-01-19 EP claimed
US-5225510-A Hydrolysis of silane monomer in the presence of acid catalysts followed by basic neutralization DOW CORNING CORPORATION (US) 1993-07-06 US claimed
US-5209775-A Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-05-11 US claimed
US-5205860-A Mixture of alkyltrioxysilane, coupling agents, and endcapped polysiloxane DOW CORNING CORPORATION (US) 1993-04-27 US claimed
EP-0388167-A1 Hybrid fibers and process for producing the same, and fiber-reinforced metals reinforced therewith UBE INDUSTRIES, LTD. (JP) 1990-09-19 EP claimed
US-4938827-A Preparation of a silicone rubber-polyester composite products HEWLETT-PACKARD COMPANY (US) 1990-07-03 US claimed