SCHEMBL377101

SCHEMBL377101

CCCCCCCCCCC[Si](OC)(OC)OC

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
TSHR P16473 4/20 0.44
THRB P10828 1/20 0.44
EPHX1 P07099 1/20 0.38
DNM1 Q05193 6/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC22A1 O15245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108513 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
SCHEMBL17003993 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
SCHEMBL11213774 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
SCHEMBL1780545 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
SCHEMBL35912 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
SCHEMBL6756329 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
SCHEMBL304612 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
SCHEMBL9931816 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
Hexane SCHEMBL6049081 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1
SCHEMBL57407 1.00 LMNA (0.65) LMNATSHRTHRBEPHX1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 697 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES CHAN, Hardy Wai Hong (TW) 2026-01-01 US claimed
CN-119331433-B High-dispersibility phthalocyanine pigment and preparation method thereof 淄博福颜化工集团有限公司 2025-03-21 CN claimed
CN-119331433-A High-dispersibility phthalocyanine pigment and preparation method thereof 淄博福颜化工集团有限公司 2025-01-21 CN claimed
WO-2024263122-A1 SUPERHYDROPHOBIC AND SUPEROLEOPHILIC COMPOSITE SPONGE MATERIAL AND THE PRODUCTION METHOD THEREOF AKDENIZ UNIVERSITESI (TR) 2024-12-26 WO claimed
CN-118547402-B Para-aramid spinning oil and preparation method thereof 烟台锐泽化学品有限公司 2024-11-01 CN claimed
CN-118547402-A Para-aramid spinning oil and preparation method thereof 烟台锐泽化学品有限公司 2024-08-27 CN claimed
EP-4358119-A2 IMPROVED SELF-ASSEMBLED MONOLAYER BLOCKING WITH INTERMITTENT AIR-WATER EXPOSURE Applied Materials, Inc. (US) 2024-04-24 EP claimed
CN-115926418-B Chemical-resistant and high-temperature-resistant basalt fiber composite material 四川衡耀复合材料科技有限公司 2024-03-26 CN claimed
CN-112239209-B Drug delivery via pore-modified mesoporous silica nanoparticles 奈力生医股份有限公司 2024-01-12 CN claimed
CN-117334560-A Improved self-assembled monolayer blocking with intermittent air-water exposure 应用材料公司 2024-01-02 CN claimed
WO-2013076035-A1 MIXTURES, PARTICULARLY LOW IN VOLATILE ORGANIC COMPOUNDS (VOC), OF OLEFINICALLY FUNTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXY SILANES EVONIK DEGUSSA GMBH (DE) 2013-05-30 WO claimed
WO-2013076032-A1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2013-05-30 WO claimed
CN-102816463-A Silane-containing pigment particles for electrophoretic display, electrophoretic fluid and electrophoretic display device SIPIX IMAGING INC 2012-12-12 CN claimed
CN-102015837-B Sulfur modified silanes for the elaboration of high refractive index materials ESSILOR INT 2012-12-05 CN claimed
CN-102015837-A Sulfur modified silanes for the elaboration of high refractive index materials ESSILOR INT 2011-04-13 CN claimed
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
CN-1681880-A Organosilicon compounds and blends for treating silica DOW CORNING (US) 2005-10-12 CN claimed
CN-1681893-A Hydrophobing silica with organosilicon compounds and blends thereof DOW CORNING (US) 2005-10-12 CN claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 LMNA 2542/4885TSHR 2005/4885THRB 3599/4885
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES AQP4, ABCB1, SRMS LMNA 1004/4885TSHR 3081/4885THRB 3746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.