Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL11482698 | 0.96 | CASP3 (0.54) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL11527522 | 0.79 | NPC1 (0.64) | CASP3SENP8SENP7SENP6HPGD | |
| Iodomethane SCHEMBL11477652 | 0.78 | RAB9A (0.54) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL20918141 | 0.78 | NPSR1 (0.58) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL27817990 | 0.78 | NPC1 (0.60) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL30620627 | 0.78 | NPC1 (0.60) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL10697623 | 0.77 | SMN1; SMN2 (0.57) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL6708905 | 0.77 | RAB9A (0.50) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL11234908 | 0.77 | NPC1 (0.59) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL20509994 | 0.77 | SMN1; SMN2 (0.63) | CASP3SENP8SENP7SENP6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4184040-A | ANTIARRHYTHMIA AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1980-01-15 | — | — | US | disclosed |
| US-4182891-A | ENZYME INHIBITORS, IMMUNOSUPPRESSANTS, CONTROL OF NEOPLASTIC GROWTH | MERRELL TORAUDE ET COMPAGNIE (FR) | 1980-01-08 | — | — | US | disclosed |