Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LOX | P28300 | 1/20 | 0.47 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.47 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294539 | 0.89 | ACSS2 (0.71) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL11474801 | 0.86 | ACSS2 (0.62) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL11476660 | 0.85 | ACSS2 (0.61) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL11475654 | 0.85 | MAPT (0.78) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL21294446 | 0.84 | LMNA (0.61) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| Water SCHEMBL11490923 | 0.84 | MAPT (0.77) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL21294461 | 0.84 | ACSS2 (0.62) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL21294463 | 0.83 | ACSS2 (0.65) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL21294470 | 0.81 | ACSS2 (0.62) | ACSS2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL11483889 | 0.81 | MAPT (0.66) | ACSS2MAPTALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207317-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |