Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459830 | 0.86 | MAPT (0.50) | SMN1; SMN2ALDH1A1ARKDM4EMEN1 | |
| SCHEMBL8803364 | 0.82 | SLC22A12 (0.45) | FNTAFNTBPGGT1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL11458038 | 0.82 | CYP19A1 (0.54) | FNTAFNTBPGGT1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL6054468 | 0.81 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL3179011 | 0.79 | PLCG1 (0.47) | RAB9ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL30209361 | 0.77 | PLCG1 (0.46) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11473016 | 0.77 | RAB9A (0.42) | RAB9AFNTAFNTBPGGT1BDYRK1A | |
| SCHEMBL1867048 | 0.77 | DYRK1A (0.55) | DYRK1ACLK4ARKDM4EHTT | |
| SCHEMBL9038839 | 0.77 | RAB9A (0.59) | RAB9AFNTAFNTBPGGT1BDYRK1A | |
| SCHEMBL8561327 | 0.75 | POLB (0.73) | RAB9AFNTAFNTBPGGT1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229457-A | TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4229457-A | TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4187379-A | ANTIAMNESIA AGENTS | WARNER-LAMBERT COMPANY (US) | 1980-02-05 | — | — | US | disclosed |