Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11844279 | 0.89 | HTR1A (0.53) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL11605905 | 0.88 | HTR1A (0.52) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL11819712 | 0.84 | DRD2 (0.50) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL11606084 | 0.84 | HTR1A (0.48) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL11827053 | 0.84 | DRD2 (0.50) | HTR1ADRD2DRD3DRD4HTR2A | |
| Hydrochloric Acid SCHEMBL11612047 | 0.83 | HTR1A (0.47) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL11852185 | 0.83 | TACR1 (0.50) | HTR1ADRD2DRD3DRD4HTR2A | |
| Hydrochloric Acid SCHEMBL11825440 | 0.83 | DRD2 (0.48) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL11856025 | 0.81 | HTR1A (0.52) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL11829418 | 0.81 | HTR1A (0.66) | HTR1ADRD2DRD3DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235914-A | ANTIPSYCHOTIC, HYPOTENSIVE, DEPRESSANTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-11-25 | — | — | US | disclosed |