Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985114 | 0.69 | ALOX5 (0.46) | ALOX5GAAMAPTNPSR1TDP1 | |
| SCHEMBL9933931 | 0.68 | ALOX5 (0.45) | ALOX5GAAMAPTNPSR1TDP1 | |
| SCHEMBL5263865 | 0.68 | ALOX5 (0.41) | ALOX5GAAMAPTNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL5316041 | 0.68 | ALOX5 (0.45) | ALOX5GAAMAPTNPSR1TDP1 | |
| SCHEMBL3637187 | 0.67 | ALOX5 (0.48) | ALOX5GAAMAPTKDM4ENPSR1 | |
| SCHEMBL9934059 | 0.67 | ALOX5 (0.48) | ALOX5GAAMAPTKDM4ENPSR1 | |
| Phenoxazine SCHEMBL2957325 | 0.67 | ALOX5 (0.74) | ALOX5GAAMAPTKDM4ENPSR1 | |
| SCHEMBL9934328 | 0.67 | ALOX5 (0.43) | ALOX5GAAMAPTNPSR1MEN1 | |
| SCHEMBL5261512 | 0.67 | ALOX5 (0.43) | ALOX5GAAMAPTNPSR1TDP1 | |
| SCHEMBL9933935 | 0.67 | ALOX5 (0.43) | ALOX5GAAMAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110045100-A1 | Antimalarial Quinolines and Methods of Use Thereof | GEORGETOWN UNIVERSITY (US) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045100-A1 | Antimalarial Quinolines and Methods of Use Thereof | NQO2, QTRT1, QTRT2 | ALOX5 1134/4885GAA 276/4885MAPT 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.