SCHEMBL11477258

SCHEMBL11477258

CCCCN(CCCC)c1ccc(C(=O)c2ccc(OCC)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
NPC1 O15118 3/20 0.50
EGFR P00533 1/20 0.49
ERBB2 P04626 1/20 0.49
PARP10 Q53GL7 1/20 0.49
ALDH1A1 P00352 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
LMNA P02545 2/20 0.48
MAPK1 P28482 1/20 0.48
HPGD P15428 2/20 0.47
RAB9A P51151 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALOX15 P16050 1/20 0.47
RECQL P46063 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TSHR P16473 1/20 0.47
PLK1 P53350 1/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11478452 0.90 L3MBTL1 (0.54) EGFRERBB2ALDH1A1L3MBTL1RAB9A
SCHEMBL1827424 0.87 EGFR (0.59) NPC1EGFRERBB2ALDH1A1HPGD
SCHEMBL7187972 0.87 NQO1 (0.54) KMT2ANPSR1NPC1ALDH1A1LMNA
SCHEMBL9749949 0.87 MEN1 (0.50) KMT2ANPSR1EGFRERBB2ALDH1A1
SCHEMBL11485414 0.84 KMT2A (0.61) KMT2ANPSR1NPC1PARP10ALDH1A1
SCHEMBL11475947 0.83 EGFR (0.60) KMT2AEGFRERBB2ALDH1A1HPGD
SCHEMBL11491657 0.83 TSHR (0.49) ALDH1A1L3MBTL1LMNARAB9AMAPT
SCHEMBL29138375 0.82 EGFR (0.54) NPC1EGFRERBB2ALDH1A1HPGD
SCHEMBL11488068 0.82 KMT2A (0.51) KMT2ANPSR1NPC1PARP10ALDH1A1
SCHEMBL5281386 0.81 HPGD (0.56) NPC1EGFRERBB2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4220356-A Recording materials containing chromenoindoles FUJI PHOTO FILM CO., LTD. (JP) 1980-09-02 US disclosed