Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147728 | 0.78 | NR1H2 (0.53) | ESR1ESR2NR1H2NR1H3MEN1 | |
| SCHEMBL9862805 | 0.78 | NR1H2 (0.37) | ESR1ESR2NR1H2NR1H3MEN1 | |
| SCHEMBL3317837 | 0.78 | NR1H2 (0.37) | ESR1ESR2NR1H2NR1H3MEN1 | |
| SCHEMBL63526 | 0.76 | ESR1 (0.70) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL2290391 | 0.75 | NR1H2 (0.42) | ESR1ESR2NR1H2NR1H3MEN1 | |
| SCHEMBL15302676 | 0.75 | NR1H2 (0.39) | ESR1ESR2NR1H2NR1H3MEN1 | |
| SCHEMBL17292829 | 0.75 | NR1H2 (0.35) | ESR1ESR2NR1H2NR1H3MEN1 | |
| SCHEMBL9715855 | 0.75 | NR1H2 (0.35) | ESR1ESR2NR1H2NR1H3MEN1 | |
| SCHEMBL723613 | 0.75 | ALDH1A1 (0.38) | NR1H2NR1H3MAPTHPGDALDH1A1 | |
| SCHEMBL12191039 | 0.74 | ESR1 (0.75) | ESR1ESR2NR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481056-A | Process for the preparation of polyolefins | TOSOH CORPORATION (JP) | 1996-01-02 | — | — | US | disclosed |