Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27754049 | 0.81 | PTGS2 (0.46) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11492583 | 0.80 | NLRP3 (0.39) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL19019142 | 0.78 | ELANE (0.46) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL27078157 | 0.76 | NLRP3 (0.43) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL27078153 | 0.76 | NLRP3 (0.43) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL30175030 | 0.76 | NLRP3 (0.43) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL15516099 | 0.75 | MAPT (0.51) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL15515197 | 0.75 | MAPT (0.51) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11478255 | 0.73 | PTGS2 (0.42) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL710531 | 0.73 | KCNH2 (0.51) | PTGS2NLRP3ALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006153-A1 | N-substituted haloacetanilides, process for their preparation, herbicidical agents containing such haloacetanilides, process for the preparation of herbicidical agents, N-ethylanilines, N-(2-hydroxyalkyl)-anilines and processes for the preparation of N-ethylanilines and N-(2-hydroxyalkyl)-anilines | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |