Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452608 | 0.95 | TGFBR1 (0.72) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7381132 | 0.93 | TGFBR1 (0.67) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9196852 | 0.90 | ATM (0.67) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9436323 | 0.90 | TGFBR1 (0.63) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9701303 | 0.86 | TGFBR1 (0.62) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11475818 | 0.86 | WDR5 (0.56) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17767606 | 0.85 | TGFBR1 (0.61) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27309763 | 0.85 | ATM (0.61) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11482604 | 0.85 | MAPT (0.59) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11490578 | 0.85 | WDR5 (0.55) | ATMTGFBR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186205-A | ANTIARTHRITIC AGENTS | SMITHKLINE CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |