Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 5/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325018 | 0.79 | HRH2 (0.43) | HRH2HRH4HRH3QPCTLMNA | |
| SCHEMBL11101330 | 0.74 | FDPS (0.43) | HRH2HRH4HRH3QPCT | |
| SCHEMBL11526674 | 0.74 | L3MBTL1 (0.51) | HRH2HRH4HRH3LMNA | |
| Metiamide SCHEMBL11363901 | 0.73 | HRH2 (0.39) | HRH2HRH4HRH3LMNA | |
| SCHEMBL11318905 | 0.73 | POLB (0.43) | HRH2HRH4HRH3QPCTRECQL | |
| SCHEMBL11477437 | 0.72 | GCK (0.30) | — | |
| SCHEMBL11254228 | 0.71 | L3MBTL1 (0.39) | HRH2HRH4HRH3 | |
| SCHEMBL11103342 | 0.69 | HRH4 (0.60) | HRH2HRH4HRH3 | |
| SCHEMBL11312823 | 0.69 | HRH2 (0.37) | HRH2HRH4HRH3QPCTLMNA | |
| SCHEMBL11101776 | 0.69 | QPCT (0.39) | HRH2HRH4HRH3QPCTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200761-A | Process for preparing N-cyano-N'methyl-N\"-{2-[(4-methyl-5-imidazolyl)-methylthio]-ethyl} guanidine | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1980-04-29 | — | — | US | disclosed |