Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438524 | 1.00 | BLM (0.49) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL11482382 | 0.85 | BLM (0.58) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL11444163 | 0.85 | BLM (0.58) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL9000789 | 0.77 | LMNA (0.62) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL3601785 | 0.77 | LMNA (0.62) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL11443180 | 0.74 | LMNA (0.59) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL10456166 | 0.74 | BLM (0.59) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL7941836 | 0.74 | FABP3 (0.57) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL778017 | 0.74 | LMNA (0.46) | BLMTSHRLMNAFABP3FABP4 | |
| SCHEMBL29630154 | 0.74 | LMNA (0.46) | BLMTSHRLMNAFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218380-A | OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |