SCHEMBL778017

SCHEMBL778017

CC(C)c1ccc(C(C)C)c(C(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
TRPA1 O75762 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
PTGS1 P23219 2/20 0.44
CACNA1C Q13936 1/20 0.44
HTT P42858 3/20 0.43
ALOX12 P18054 3/20 0.43
HIF1A Q16665 3/20 0.43
FABP3 P05413 2/20 0.43
FABP4 P15090 2/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
FABP5 Q01469 1/20 0.41
RNASEH1 O60930 1/20 0.40
SLC6A2 P23975 2/20 0.39
HTR2B P41595 2/20 0.39
CHRM1 P11229 1/20 0.39
ADRA1A P35348 1/20 0.39
TYR P14679 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630154 1.00 LMNA (0.46) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL9098411 0.87 HTT (0.43) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL26814968 0.85 LMNA (0.40) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL11770401 0.85 LMNA (0.40) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL9684224 0.85 TRPA1 (0.43) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL26938106 0.84 LMNA (0.37) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL20368240 0.84 HIF1A (0.45) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL8542062 0.82 GABRA1 (0.35) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL8750483 0.82 LMNA (0.38) LMNATRPA1GABRA1GABRB2PTGS1
SCHEMBL29923781 0.80 KIF11 (0.40) LMNATRPA1GABRA1GABRB2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0061760-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-03-02 EP claimed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
CN-117940489-A Process for preparing asphalt mixture composition 巴斯夫欧洲公司 2024-04-26 CN disclosed
CN-117916425-A Process for preparing an asphalt mixture composition, asphalt mixture composition and use thereof 巴斯夫欧洲公司 2024-04-19 CN disclosed
CN-117597402-A Use of asphalt compositions in weathering applications 巴斯夫欧洲公司 2024-02-23 CN disclosed
WO-2023211990-A1 BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA V1.8 FOR THE TREATMENT OF PAIN SITEONE THERAPEUTICS, INC. (US) 2023-11-02 WO disclosed
EP-3663351-B1 THERMOSETTING RESIN COMPOSITION, AND PREPREG AND METAL FOIL CLAD LAMINATE PREPARED FROM SAME SHENGYI TECHNOLOGY CO LTD (CN) 2023-08-23 EP disclosed
CN-111346667-B Molecular sieve catalyst for synthesizing triisopropylbenzene, preparation method and method for synthesizing triisopropylbenzene 中国石油天然气股份有限公司 2023-04-25 CN disclosed
US-20230045778-A9 HETEROGENEOUS HYDROGEN-CATALYST SOLID FUEL REACTION MIXTURE AND REACTOR BRILLIANT LIGHT POWER, INC. (US) 2023-02-09 US disclosed
EP-0418648-A1 4-Hydroxytetrahydropyran-2-ones as well as the corresponding dehydroxy carbon acid derivatives, salts and esters, process for their preparation, pharmaceutical preparations as well as precursors HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-27 EP disclosed
CN-1007814-B Linear salicylic acid copolymer and method for producing metal salt thereof, and color-developing agent containing copolymer metal salt, and color-developing paper using the same MITSUI TOATSU CHEMICALS (JP) 1990-05-02 CN disclosed
US-4783521-A Linear salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal-resins of the copolymers MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-11-08 US disclosed
CN-87100709-A Linear salicylic acid copolymer and method for producing metal salt thereof, and color-developing agent containing copolymer metal salt, and color-developing paper using the same 1987-09-02 CN disclosed
EP-0233450-A2 Linear salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal-resins of the copolymers, and color-developing sheets employing the agents MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-08-26 EP disclosed
US-4599470-A LAYERED CLAY AS CATALYST THE BRITISH PETROLEUM COMPANY P.L.C. (GB) 1986-07-08 US disclosed
US-4491664-A Process for the production of ergot alkaloids SANDOZ LTD. (CH) 1985-01-01 US disclosed
US-4041226-A Chromium tris-diorgano-orthophosphate-alkyl aluminum halide catalysts for olefin polymerization and alkylation of aromatic compounds ANDERSON DEVELOPMENT COMPANY (US) 1977-08-09 US disclosed
US-4005156-A Novel flame retardant compositions of matter UNIVERSAL OIL PRODUCTS COMPANY (US) 1977-01-25 US disclosed
US-3969272-A Chromium tris-diorgano-orthophosphate-alkyl aluminum halide catalysts for olefin polymerization and alkylation of aromatic compounds ANDERSON DEVELOPMENT COMPANY (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 LMNA 4529/4885TRPA1 1999/4885GABRA1 2837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.