Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 5/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.34 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 6/20 | 0.34 |
| ▸ | CDK14 | O94921 | 2/20 | 0.33 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477939 | 0.86 | BTK (0.38) | KRASJAK3ALDH1A1HPGDKMT2A | |
| SCHEMBL11475949 | 0.81 | ALDH1A1 (0.41) | KRASALDH1A1KMT2A | |
| SCHEMBL11475004 | 0.79 | GSK3B (0.41) | KRASALDH1A1TET3KMT2AFBXL19 | |
| SCHEMBL16640400 | 0.77 | MAPK1 (0.40) | KMT2A | |
| SCHEMBL11476568 | 0.75 | CHRNB2 (0.36) | OPRK1KRASJAK3TET3KMT2A | |
| SCHEMBL11468538 | 0.73 | JAK3 (0.33) | KRASJAK3TET3KMT2AFBXL19 | |
| SCHEMBL11472517 | 0.73 | GSK3B (0.37) | JAK3 | |
| SCHEMBL11470276 | 0.72 | CHRNB2 (0.49) | KRASJAK3KMT2ABTK | |
| SCHEMBL11469949 | 0.72 | BTK (0.36) | KRASJAK3ALDH1A1BTK | |
| SCHEMBL11468236 | 0.71 | SRC (0.50) | JAK3ALDH1A1TET3KMT2AFBXL19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189484-A | Antihypertensive quinazoline derivatives | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-19 | — | — | US | disclosed |