Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570294 | 0.81 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL105590 | 0.78 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL4808799 | 0.78 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL2004098 | 0.78 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL7305175 | 0.78 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL11305463 | 0.78 | CCNC (0.44) | LMNATDP1 | |
| SCHEMBL6664957 | 0.77 | NR1I2 (0.40) | — | |
| SCHEMBL11478548 | 0.77 | KCNH2 (0.40) | — | |
| SCHEMBL11483215 | 0.77 | KCNH2 (0.50) | LMNA | |
| SCHEMBL11474709 | 0.75 | GRM5 (0.57) | CHRNB2CHRNA4CHRNA3CHRNB1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220577-A | Iodopropargyl pyridyl and picolinyl ethers and thioethers as paint fungicides | GIVAUDAN CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| US-4170704-A | STABLE TO HEAT AND LIGHT | GIVAUDAN CORPORATION (US) | 1979-10-09 | — | — | US | disclosed |