Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.57 |
| ▸ | AURKA | O14965 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188631 | 0.84 | AURKA (0.59) | LRRK2AURKAKDM4EGAAHPGD | |
| SCHEMBL8329356 | 0.80 | FLT1 (0.47) | LRRK2AURKAKDM4EGAAHPGD | |
| SCHEMBL395135 | 0.80 | KDM4E (0.55) | LRRK2AURKAKDM4EGAAHPGD | |
| SCHEMBL30804592 | 0.80 | KDM4E (0.55) | LRRK2AURKAKDM4EGAAHPGD | |
| SCHEMBL30804597 | 0.80 | KDM4E (0.55) | LRRK2AURKAKDM4EGAAHPGD | |
| SCHEMBL1712793 | 0.80 | ADRA2A (0.57) | KDM4EADRA2AGAAADRA2BADRA2C | |
| SCHEMBL16481161 | 0.79 | KDM4E (0.49) | LRRK2AURKAKDM4EGAAHPGD | |
| SCHEMBL24681745 | 0.78 | KDR (0.51) | LRRK2AURKAKDM4EGAAHPGD | |
| SCHEMBL16481316 | 0.78 | LMNA (0.62) | LRRK2AURKAKDM4EGAAHPGD | |
| SCHEMBL4193666 | 0.78 | KDM4E (0.62) | LRRK2AURKAKDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206215-A | Antimicrobial bis-[4-(substituted-amino)-1-pyridinium]alkanes | STERLING DRUG INC. (US) | 1980-06-03 | — | — | US | disclosed |