Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926521 | 0.87 | ALDH1A1 (0.69) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL6029533 | 0.86 | ALDH1A1 (0.68) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL19726938 | 0.86 | HPGD (0.73) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL5116644 | 0.85 | HPGD (0.71) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL21630176 | 0.85 | HPGD (0.71) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL29410065 | 0.84 | ALDH1A1 (0.74) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL2115850 | 0.82 | HPGD (1.00) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL28180601 | 0.82 | HPGD (0.68) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL6289033 | 0.81 | ALDH1A1 (0.70) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL9912447 | 0.81 | ALDH1A1 (0.70) | HPGDALDH1A1POLBMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200652-A | ADRENERGIC BLOCKING AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-04-29 | — | — | US | disclosed |
| US-4115409-A | CARDIOVASCULAR DISORDERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |