Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410065 | 0.87 | ALDH1A1 (0.74) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| SCHEMBL23012380 | 0.87 | EPHX2 (0.65) | ALDH1A1HPGDPOLBL3MBTL1KDM4E | |
| SCHEMBL11479230 | 0.86 | HPGD (0.69) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| SCHEMBL11882501 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| SCHEMBL6289033 | 0.84 | ALDH1A1 (0.70) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| SCHEMBL9912447 | 0.84 | ALDH1A1 (0.70) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| SCHEMBL20189300 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| SCHEMBL2638805 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| SCHEMBL14511323 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| SCHEMBL6070205 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983748-A | Chemical intermediates for polysaccharide aldehydes; wet strength paper additive | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-01-08 | — | — | US | claimed |
| EP-1478653-B1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| US-6995143-B2 | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2006-02-07 | — | — | US | disclosed |
| EP-1478653-A1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | Basilea Pharmaceutica AG (CH) | 2004-11-24 | — | — | EP | disclosed |
| US-20030212011-A1 | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2003-11-13 | — | — | US | disclosed |
| WO-2003072588-A1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2003-09-04 | — | — | WO | disclosed |
| US-4983748-A | Chemical intermediates for polysaccharide aldehydes; wet strength paper additive | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-01-08 | — | — | US | disclosed |
| US-4804769-A | PAPER ADDITIVES | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4741804-A | Polysaccharide derivatives containing aldehyde groups, their preparation from the corresponding acetals and use as paper additives | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-05-03 | — | — | US | disclosed |
| US-4703116-A | WET STRENGTH, DRY STRENGTH | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1987-10-27 | — | — | US | disclosed |
| EP-0232851-A2 | Polysaccaride derivatives containing aldehyde groups, corresponding acetals and use as paper additives | National Starch and Chemical Investment Holding Corporation (US) | 1987-08-19 | — | — | EP | disclosed |
| EP-0010231-B1 | POLYPHOSPHAZENE POLYMERS CONTAINING N-SUBSTITUTED AMIDO AND IMIDO SUBSTITUENTS AND PROCESS FOR THEIR PREPARATION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4258196-A | REACTING THE ANION OF A PRIMARY OR SECONDARY 2-HALOACETAMIDE WITH AN ALKYLATING AGENT | MONSANTO COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4218557-A | PROTECTIVE COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| EP-0010231-A1 | Polyphosphazene polymers containing N-substituted amido and imido substituents and process for their preparation | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |
| US-3972928-A | Regulating plant growth with quaternary phosphonium aliphatic carboxamide salts | BAYCHEM CORPORATION (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | HPGD, KRT18, PTGS1 | ALDH1A1 208/4885HPGD 1/4885POLB 617/4885 |
| US-20030212011-A1 | Macrolides with antibacterial activity | MRPL21, RPS21, MRPS18A | ALDH1A1 3345/4885HPGD 4573/4885POLB 3397/4885 |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | KRT18, TYR, CRYAA | ALDH1A1 539/4885HPGD 386/4885POLB 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.