Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469344 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11479300 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11507044 | 0.88 | KMT2A (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11506506 | 0.88 | KMT2A (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11506505 | 0.88 | KMT2A (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11330704 | 0.83 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11547947 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11548568 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11550110 | 0.81 | MEN1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF | |
| SCHEMBL11506608 | 0.81 | CHRM2 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |