Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | RXRG | P48443 | 1/20 | 0.52 |
| ▸ | ADH5 | P11766 | 1/20 | 0.52 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475605 | 0.83 | TBXAS1 (0.71) | TBXAS1CYP3A4HDAC3MAPK1ADRA1A | |
| SCHEMBL7434598 | 0.81 | TBXAS1 (0.68) | TBXAS1CYP3A4ADH5BAZ2BENPP2 | |
| SCHEMBL11484688 | 0.81 | TBXAS1 (0.68) | TBXAS1CYP3A4CYP2D6CYP2C9BAZ2B | |
| SCHEMBL10762282 | 0.81 | TBXAS1 (0.68) | TBXAS1CYP3A4CYP2D6CYP2C9ADH5 | |
| SCHEMBL11449452 | 0.80 | CYP2D6 (0.68) | TBXAS1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11477536 | 0.80 | TBXAS1 (0.66) | TBXAS1CYP3A4 | |
| SCHEMBL28108298 | 0.78 | CYP3A4 (0.65) | TBXAS1CYP3A4CYP2D6CYP2C9BAZ2B | |
| Hydrochloric Acid SCHEMBL11477573 | 0.78 | TBXAS1 (1.00) | TBXAS1CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8392830 | 0.78 | CYP3A4 (0.69) | TBXAS1CYP3A4CYP2D6CYP2C9ADH5 | |
| SCHEMBL7275362 | 0.78 | TBXAS1 (0.63) | TBXAS1CYP3A4CYP2D6CYP2C9ADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4226878-A | ANTIINFLAMMATORY, HYPOTENSIVES, ANTIHISTAMINES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1980-10-07 | — | — | US | disclosed |