Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.47 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477037 | 0.86 | TBXAS1 (0.50) | TBXAS1KDM4EMEN1MITFALDH1A1 | |
| SCHEMBL7404987 | 0.84 | MAPT (0.63) | TBXAS1KDM4EMEN1MITFALDH1A1 | |
| SCHEMBL11477428 | 0.82 | TBXAS1 (0.67) | TBXAS1MEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL11479530 | 0.82 | GLS (0.49) | TBXAS1KDM4EMEN1MITFALDH1A1 | |
| SCHEMBL11479727 | 0.81 | TBXAS1 (1.00) | TBXAS1MEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL29239308 | 0.79 | TBXAS1 (0.62) | TBXAS1ALDH1A1CYP19A1 | |
| SCHEMBL18746522 | 0.78 | CYP2D6 (0.71) | TBXAS1KDM4EMEN1MITFALDH1A1 | |
| SCHEMBL28108298 | 0.78 | CYP3A4 (0.65) | TBXAS1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL27469498 | 0.78 | ALOX5 (0.56) | TBXAS1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5089219 | 0.77 | HTT (0.60) | KDM4EMEN1MITFALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4226878-A | ANTIINFLAMMATORY, HYPOTENSIVES, ANTIHISTAMINES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1980-10-07 | — | — | US | disclosed |