Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483294 | 0.94 | POLB (0.49) | POLBKMT2AGAAATMKDM4E | |
| SCHEMBL11487438 | 0.79 | ALDH1A1 (0.55) | POLBKMT2AGAAKDM4EBLM | |
| SCHEMBL26697229 | 0.78 | KMT2A (0.54) | POLBKMT2AGAAATMKDM4E | |
| SCHEMBL4649774 | 0.76 | NPC1 (0.53) | POLBGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11480568 | 0.74 | MEN1 (0.50) | POLBKMT2AGAAKDM4EMEN1 | |
| SCHEMBL11316181 | 0.74 | GPR27 (0.57) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11131058 | 0.73 | POLB (0.63) | POLBKMT2AGAAKDM4EMEN1 | |
| SCHEMBL8898256 | 0.73 | NPC1 (0.55) | POLBGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28765021 | 0.73 | KMT2A (0.55) | KMT2AGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL28051040 | 0.72 | KMT2A (0.57) | POLBKMT2AGAAATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006154-A1 | Monoazo pigments and their use in colouring high molecular-weight organic material | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |