Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11491168 | 0.91 | RIPK1 (0.36) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL11478506 | 0.90 | MAOB (0.34) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL11482056 | 0.78 | ADRB2 (0.46) | ADRB2ADRB1MAPTMAOB | |
| SCHEMBL11374129 | 0.78 | KDR (0.35) | — | |
| SCHEMBL11385079 | 0.78 | PTPN1 (0.34) | CYP19A1 | |
| SCHEMBL11480167 | 0.76 | CNR2 (0.43) | — | |
| SCHEMBL11481757 | 0.76 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL11381338 | 0.76 | KDR (0.36) | — | |
| SCHEMBL11383688 | 0.76 | RIPK1 (0.33) | MAPTCYP19A1 | |
| SCHEMBL11492461 | 0.74 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235913-A | ANALGESICS, TRANQUILIZERS | PFIZER INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4165323-A | ANALGESICS, TRANQUILIZERS | PFIZER INC. (US) | 1979-08-21 | — | — | US | disclosed |
| US-4118559-A | CNS AGENTS, ANALGESICS, TRANQUILIZERS | PFIZER INC. (US) | 1978-10-03 | — | — | US | disclosed |