Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cromitrile SCHEMBL11475038 | 0.99 | GPR35 (0.46) | GPR35LMNATDP1HIF1AMEN1 | |
| Cromitrile SCHEMBL11480428 | 0.98 | GPR35 (0.46) | GPR35LMNATDP1HIF1AMEN1 | |
| SCHEMBL11489129 | 0.89 | GPR35 (0.53) | GPR35LMNATDP1HIF1AMEN1 | |
| SCHEMBL11773782 | 0.89 | GPR35 (0.56) | GPR35LMNATDP1HIF1AMEN1 | |
| SCHEMBL11477011 | 0.89 | GPR35 (0.48) | GPR35LMNATDP1HIF1AMEN1 | |
| Cromitrile Sodium SCHEMBL636215 | 0.81 | GPR35 (0.46) | GPR35LMNATDP1HIF1AMEN1 | |
| Cromitrile Sodium SCHEMBL1649767 | 0.79 | GPR35 (0.46) | GPR35LMNATDP1HIF1AMEN1 | |
| SCHEMBL11482479 | 0.79 | GPR35 (0.57) | GPR35LMNATDP1HIF1AMEN1 | |
| SCHEMBL11348725 | 0.77 | GPR35 (0.78) | GPR35LMNATDP1HIF1AMEN1 | |
| SCHEMBL11478258 | 0.76 | GPR35 (0.76) | GPR35LMNATDP1HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238495-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | MILES LABORATORIES, INC. (US) | 1980-12-09 | — | — | US | claimed |
| US-4238495-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | MILES LABORATORIES, INC. (US) | 1980-12-09 | — | — | US | disclosed |