Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475707 | 0.78 | HPGD (0.44) | KDM4EALDH1A1HSD17B10GABRA1HPGD | |
| SCHEMBL11512880 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1LMNACTSSKMO | |
| SCHEMBL11483611 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1LMNACTSSKMO | |
| SCHEMBL31307043 | 0.74 | ALDH1A1 (0.55) | KDM4EALDH1A1LMNACTSSKMO | |
| SCHEMBL11478689 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1LMNACTSSKMO | |
| SCHEMBL11470852 | 0.73 | MAOB (0.46) | KDM4EALDH1A1NOTUMHSD17B10MAOB | |
| SCHEMBL11510818 | 0.72 | KDM4E (0.47) | KDM4EALDH1A1LMNAKMOIDO1 | |
| SCHEMBL11483535 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1LMNACTSSKMO | |
| SCHEMBL2022591 | 0.70 | PIK3CD (0.47) | KDM4EALDH1A1LMNAHSD17B10CYP1A2 | |
| SCHEMBL11158748 | 0.69 | SCN5A (0.55) | KDM4EALDH1A1NOTUMHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209621-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |