Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510818 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1LMNAIDO1NOTUM | |
| SCHEMBL11480435 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1LMNAIDO1CTSS | |
| SCHEMBL11514797 | 0.75 | KDM4E (0.58) | KDM4EALDH1A1LMNAIDO1CTSS | |
| SCHEMBL11625891 | 0.73 | ALDH1A1 (0.59) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL11512157 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1GABRG2GABRB3GABRA5 | |
| SCHEMBL3398455 | 0.71 | ADORA2A (0.56) | IDO1CTSSNOTUMCYP1A2CYP3A4 | |
| SCHEMBL9702800 | 0.70 | KDM4E (0.62) | KDM4EALDH1A1LMNAIDO1CTSS | |
| SCHEMBL2463789 | 0.70 | KDM4E (0.55) | KDM4EALDH1A1LMNAIDO1CTSS | |
| SCHEMBL11470852 | 0.69 | MAOB (0.46) | KDM4EALDH1A1NOTUMHSD17B10MAOB | |
| SCHEMBL11478689 | 0.69 | KDM4E (1.00) | KDM4EALDH1A1LMNAIDO1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159375-A | 6- AND 7-Aryl-1,2,4-triazolo[4,3-b]-1,2,4-triazines | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |