Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6291806 | 0.98 | GABRA1 (0.43) | GABRA1GABRB2CYP3A4TSHRPIK3CA | |
| SCHEMBL5184430 | 0.83 | GABRA1 (0.55) | GABRA1GABRB2MGLLMAPT | |
| SCHEMBL15750993 | 0.83 | CYP3A4 (0.36) | GABRA1GABRB2CYP3A4TSHRPIK3CA | |
| SCHEMBL6756197 | 0.81 | ALDH1A1 (0.38) | GABRA1GABRB2CYP3A4TSHRPIK3CA | |
| SCHEMBL39547 | 0.78 | — | — | |
| SCHEMBL29565534 | 0.78 | — | — | |
| SCHEMBL595335 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2CYP3A4TSHRPIK3CA | |
| SCHEMBL1972038 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2MGLLSMN1; SMN2MAPT | |
| Iodide SCHEMBL29238182 | 0.75 | CYP3A4 (0.47) | GABRA1GABRB2CYP3A4TSHRPIK3CA | |
| Bromide SCHEMBL28472529 | 0.75 | CYP3A4 (0.47) | GABRA1GABRB2CYP3A4TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957241-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| CN-107531652-A | Aromatic diamine, intermediate thereof, and processes for producing these | 精化株式会社 | 2018-01-02 | — | — | CN | disclosed |
| EP-2738208-B1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | SHIKOKU CHEM (JP) | 2017-07-19 | — | — | EP | disclosed |
| CN-103703071-B | Coupling agent for rubber/carbon black and rubber composition for tire containing the same | SHIKOKU CHEMICALS CORP. (JP) | 2015-12-09 | — | — | CN | disclosed |
| US-9200145-B2 | Coupling agent for rubber/carbon black, and rubber composition containing same for use in tires | SHIKOKU CHEMICALS CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140155541-A1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | SHIKOKU CHEMICALS CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2738208-A1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | Shikoku Chemicals Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| CN-103703071-A | Coupling agent for rubber/carbon black and rubber composition for tire containing the same | SHIKOKU CHEM | 2014-04-02 | — | — | CN | disclosed |
| US-4242474-A | A POLYHYDROXY ACRYLIC ESTER REACTED WITH AN ISOCYANATE TERMINATED POLYOXYALKYLENE GLYCOL; BIOPOLYMERS | TERUMO CORPORATION (JP) | 1980-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | WEE1, WEE2, WASF2 | GABRA1 409/4885GABRB2 640/4885CYP3A4 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.