Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395051 | 0.82 | MAOB (0.48) | TAAR1AOC3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28952278 | 0.77 | CYP1A2 (0.46) | LTB4RCALM1TAAR1CYP1A2CYP3A4 | |
| SCHEMBL27849224 | 0.75 | CALM1 (0.44) | LTB4RCALM1TAAR1AOC3CYP1A2 | |
| SCHEMBL27548252 | 0.75 | TAAR1 (0.46) | LTB4RCALM1TAAR1CYP1A2CYP3A4 | |
| SCHEMBL27832719 | 0.75 | CALM1 (0.44) | LTB4RCALM1TAAR1CYP1A2CYP3A4 | |
| SCHEMBL31199125 | 0.75 | CALM1 (0.44) | LTB4RCALM1TAAR1CYP1A2CYP3A4 | |
| SCHEMBL27340551 | 0.73 | MAPT (0.43) | LTB4RCALM1TAAR1CYP1A2CYP3A4 | |
| SCHEMBL27502298 | 0.71 | CYP3A4 (0.45) | LTB4RCALM1TAAR1AOC3CYP1A2 | |
| SCHEMBL8941721 | 0.69 | — | — | |
| SCHEMBL11450705 | 0.68 | TRPA1 (0.43) | CALM1TAAR1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4192803-A | ANTIPSYCHOTIC OR NEUROLEPTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-03-11 | — | — | US | disclosed |