Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148310 | 0.91 | PDE2A (0.41) | MEN1KMT2APDE2ACYP1A2CYP2D6 | |
| Benzene SCHEMBL1148105 | 0.85 | CYP1A2 (0.47) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| Benzene SCHEMBL1148081 | 0.84 | CYP1A2 (0.43) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| Benzene SCHEMBL1147623 | 0.83 | CYP1A2 (0.46) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| Benzene SCHEMBL1148142 | 0.83 | CYP1A2 (0.46) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| Benzene SCHEMBL1148272 | 0.82 | LMNA (0.47) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| Benzene SCHEMBL1148094 | 0.81 | CYP1A2 (0.40) | CYP1A2CYP2D6CYP2C9CYP2C19PPARD | |
| Benzene SCHEMBL1148127 | 0.79 | RAB9A (0.39) | CYP1A2CYP2D6CYP2C9CYP2C19PRMT5 | |
| Benzene SCHEMBL1148150 | 0.77 | CYP1A2 (0.36) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1148078 | 0.76 | CYP1A2 (0.40) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884103-B2 | such as N-(4-Chloro-phenyl)-2-methyl-2-phenylmethanesulfonylamino-3-(4-[1,2,4]triazol-1-yl-phenoxy)-propionamide, used for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-08 | — | — | US | claimed |
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-07-05 | — | — | US | claimed |
| JP-2007504108-A | — | — | 2007-03-01 | — | — | JP | claimed |
| EP-1660441-A2 | N-SULFONYL-ALPHA-AMINO-ACID DERIVATIVES | Syngenta Participations AG (CH) | 2006-05-31 | — | — | EP | claimed |
| WO-2005021490-A2 | N-SULFONYL-α-AMINO-ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-03-10 | — | — | WO | claimed |
| US-7884103-B2 | such as N-(4-Chloro-phenyl)-2-methyl-2-phenylmethanesulfonylamino-3-(4-[1,2,4]triazol-1-yl-phenoxy)-propionamide, used for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-07-05 | — | — | US | disclosed |
| EP-1660441-A2 | N-SULFONYL-ALPHA-AMINO-ACID DERIVATIVES | Syngenta Participations AG (CH) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021490-A2 | N-SULFONYL-α-AMINO-ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | C3AR1, GLRA1, C5AR1 | MEN1 1928/4885KMT2A 2743/4885PDE2A 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.